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Table 3 Area under the curve for each biomarker as a predictor of severe sepsis and death

From: The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis

 

Outcome

 

Severe Sepsis

Death

Biomarker

AUC

95% CI

AUC

95% CI

sFlt-1

0.82*

0.76 to 0.88

0.91*

0.87 to 0.95

PAI-1

0.69

0.62 to 0.76

0.74

0.60 to 0.88

Eselectin

0.71

0.64 to 0.78

0.65

0.49 to 0.82

Icam

0.61

0.53 to 0.69

0.72

0.57 to 0.87

Vcam

0.60

0.52 to 0.69

0.57

0.35 to 0.79

  1. *the area under the curve for sFlt-1 in predicting both severe sepsis (includes patients with septic shock) and mortality was significantly greater than all other AUC values, P < 0.01.