From: The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis
Parameters | Overall |
---|---|
 | n = 221 |
Demographics | Â |
Age median, mean (SD) | 57, 58 (19) |
Race: white n (%) | 169 (76%) |
   african-american | 28 (13%) |
   Other | 24 (11%) |
Female gender n (%) | 115 (52%) |
Comorbidities n (%) | Â |
COPD | 16 (7%) |
Chronic Heart failure | 29 (13%) |
Diabetes | 63 (28%) |
Cancer | 45 (20%) |
Sepsis Syndrome n(%) | Â |
Non-infected ED patients | 14 (6%) |
Sepsis without organ dysfunction | 70 (32%) |
Severe Sepsis without shock | 66 (30%) |
Septic Shock | 71 (32%) |
Severity of Disease, median, mean (SD) | Â |
SOFA score | 2, 3 (4) |
APACHE score | 11, 12 (8) |
Lactate (mg/dL) | 1.5, 2.1(1.7) |
Marker levels on admission* median, mean (SD) | Â |
Eselectin (ng/mL) | 49.3, 67.5 (55.4) |
VCAM-1 (ng/mL) | 1,120, 1,411 (1,316) |
ICAM-1 (ng/mL) | 176, 224 (151) |
PAI-1 (ng/mL) | 40.9 64.6 (644) |
sFlt-1 (pg/mL) | 118, 194 (224) |