Figure 5
From: The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis
Comparison of biomarkers levels for survivors and non-survivors in septic shock subset. Shown here are the biomarker levels for the subset (n = 52) of patients with septic shock who had serial blood draws at 0, 24, 48 and 72 hours and were used to compare biomarker levels between survivors (n = 43) and non-survivors (n = 9). Using a linear mixed effects model, adjusting for age, gender, and co-morbid burden, we found the following estimated mean differences in biomarker levels over time comparing the non-survivors to survivors: sFlt-1 366 pg/mL (95% CI: 218 to 514, P < 0.01); PAI-1 63.2 ng/ml (38.5 to 87.8, P < 0.01); sE-selectin 24.1 ng/mL (5.5 to 42.7, P < 0.01); sICAM-1 135 ng/mL (67 to 202, P < 0.01); sVCAM-1 683 ng/mL (320 to 1046, P < 0.01).