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Figure 7 | Critical Care

Figure 7

From: Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery

Figure 7

Addition of recombinant human IL-6 to freshly isolated proximal tubules. A total of 200 ng of recombinant human (h) IL-6 was added to media with and without freshly isolated proximal tubules after 20 minutes of either normoxic or hypoxic conditions. Media human IL-6 concentration was determined after five minutes of incubation. Human IL-6 was significantly reduced in the media containing normoxic proximal tubules versus normoxic and hypoxic media without proximal tubules (*P < 0.02, n = 5 to 6). Media human IL-6 was higher in hypoxic proximal tubules versus normoxic proximal tubules (†P = 0.05, n = 6).

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Critical Care

ISSN: 1364-8535