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Table 5 Pulmonary vascular properties of vasoactive agents

From: Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review

 

CI

PVR

SVR

PVR/SVR

Tachycardia

Renala/metabolic

Vasopressors

   

Dose related

  

   NE

+

+

++

+/-

+

Lactic acidosis

   PHE

-

++

+

+

-

-

   Low-dose AVP

+/-

+/-

++

-

-

Diuresis ++

Inotropes

      

   Dobutamine

++

-

-

-

+

 

   < 5 μg/kg/min

      

   Dopamine

+

+/-

+

+

++

Natriuresis

   Epinephrine

++

-

++

-

++

Lactic acidosis

Inodilators

      

   PDE IIIs

++

-

-

-

+/-

-

   Levosimendan

++

-

-

-

-

-

  1. AVP, arginine vasopressin; NE, norepinephrine; PDE IIIs, phosphodiesterase inhibitors; PHE, phenylephrine. aRenal blood flow is likely to improve with increased cardiac output and systemic blood pressure with all agents.
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Critical Care

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