Table 1 Patient characteristics
DAA + (n= 16) | DAA - (n= 16) | P | |
|---|---|---|---|
Age (yr) | 67.4 ρ 4.0 | 67.9 ρ 2.7 | NS |
SAPS II | 62.7 ± 2.8 | 61.5 ± 3.7 | NS |
LOD score | 9.3 ± 0.8 | 8.4 ± 0.8 | NS |
Septicaemia (n (%)) | 9 (56%) | 11 (69%) | NS |
ICU stay (days) | 32.9 ± 8.8 | 54.2 ± 19.3 | NS |
Mortality at Day 28 (n (%)) | 7 (43%) | 8 (50%) | NS |
Type of bacterium : n (%) | |||
Gram-positive | 8 (50%) | 6 (37%) | |
Gram-negative | 5 (31%) | 6 (37%) | NS |
Others (fungi) | 3 (19%) | 6 (37%) | |
Source of infection : n (%) | |||
Pneumonia | 6 (37%) | 9 (56%) | |
Peritonitis | 5 (31%) | 2 (12.5%) | NS |
Others | 5 (31%) | 4 (25%) | |
Toll-like receptors genotyping: n | |||
Genotype of TLR-2 (Arg753Arg/Arg753Gln/Gln753Gln) | 16/0/0 | 16/0/0 | NS |
Genotype of TLR-4 (Asp299Asp/Asp299Gly/Gly299Gly) | 12/4/0 | 15/1/0 | NS |
Genotype of TLR-4 (Thr399Thr/Thr399Ile/Ile399Ile) | 12/4/0 | 15/1/0 | NS |