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Figure 4 | Critical Care

Figure 4

From: Interleukin-10 gene down-expression in circulating mononuclear cells during infusion of drotrecogin-α activated: a pilot study

Figure 4

Evolution of IFN-γ, TNF-α and IL-10 mRNA expressions in CMNCs from DAA + ( n = 16) and DAA- patients ( n = 16) between inclusion (T1) and after a 36-h DAA infusion (T2). When we compare survivors versus non survivors, there is a significant over-expression for both IFN-γ and IL-10 in DAA+ non survivors compared to DAA+ survivors (§: P = 0.038, #: P < 0.001 respectively, Mann-Whitney test). Box and whiskers plots show median and inter quartile range (25 to 75). Fold change is calculated as the ratio (T2-T1)/T1. DAA: drotrecogin-α activated.

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