Table 9 Dosing of antifungals in paediatric patients
From: Bench-to-bedside review: Therapeutic management of invasive candidiasis in the intensive care unit
Drug | Dose |
|---|---|
Amphotericin B deoxycholate | 1 mg/kg daily |
Liposomal amphotericin B | 3 mg/kg daily |
Lipid complex amphotericin B | 3 to 5 mg/kg daily (> 1 month old) |
Fluconazole | 12 mg/kg daily |
Caspofungin | 50 mg/m2, with a loading dose of 70 mg/m2 (> 1 year old) |
Micafungin | 2 mg/kg daily in children if <40 kg |
Anidulafungin | 1.5 mg/kg/day, with a loading dose of 3 mg/kg/day (in children 2 to 17 years old) |
Voriconazole | 7 mg/kg every 12 hours, up to age 12 years |