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Figure 2 | Critical Care

Figure 2

From: Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice

Figure 2

Flagellin triggers IκBα phosphorylation and degradation in mouse organs. Phosphorylation of inhibitor of kappaB alpha (IκBα), associated with IκBα degradation, 30 minutes after flagellin (1 μg/mouse) or saline (sham) in mouse lung, liver, gut and kidney; α-tubulin and β-actin, loading controls. Densitometric analysis, * P < 0.05 flagellin vs sham, t-test (n = 5 mice/group).

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