Table 5 Blood loss in studies comparing a balanced strategy with a saline-based strategy
Study | Group | Blood loss (ml) | P value between groups |
|---|---|---|---|
Crystalloids only | |||
Waters and colleagues [36] | Ringer's lactate | 2,300 (1,600 to 3,500) | NS |
Isotonic saline | 2,900 (1,930 to 4,000) | ||
Boldt and colleagues [16] | Ringer's lactate | 1,830 ± 380 | NS |
Isotonic saline | 1,730 ± 390 | ||
Colloids and crystalloids | |||
Kulla and colleagues [21] | HES 130/0.42 + Ringer's acetate | 1,156 ± 917 | NS |
HES 130/0.42 + modified saline | 1,228 ± 691 | ||
Boldt and colleagues [18] | HES 130/0.42 + modified RL | 1,798 ± 1,220 | NS |
HES 130/0.42 + isotonic saline | 1,557 ± 1,165 | ||
Boldt and colleagues [19] | HES 130/0.42 + modified RL | 1,510 ± 410 | NS |
HES 130/0.42 + isotonic saline | 1,380 ± 460 | ||
Boldt and colleagues [20] | HES 130/0.42 + modified RL | 1,200 ± 290 | < 0.05 |
Albumin 5% + isotonic saline | 1,520 ± 210 | ||
Boldt and colleagues [22] | HES 130/0.40 + modified RL | 1,380 ± 460 | NS |
Albumin 5% + isotonic saline | 1,510 ± 410 |