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Table 4 Cut-off values for CPA-ROSC and diagnostic accuracy

From: Who benefits most from mild therapeutic hypothermia in coronary intervention era? A retrospective and propensity-matched study

CPA-ROSC Sensitivity Specificity Positive predictive value Negative predictive value Accuracy (%)
Hypothermia group     
   18 minutes 37 (28 to 46) 91 (86 to 96) 73 (65 to 81) 69 (60 to 78) 70
   25 minutes 60 (51 to 69) 84 (77 to 91) 70 (61 to 79) 77 (69 to 85) 74
   29 minutes 70 (61 to 79) 79 (71 to 87) 68 (59 to 77) 80 (73 to 87) 75
   34 minutes 79 (71 to 87) 70 (61 to 79) 63 (54 to 72) 84 (77 to 91) 74
   45 minutes 93 (88 to 98) 40 (31 to 49) 50 (41 to 59) 90 (84 to 96) 61
   65 minutes 100 4 (1 to 8) 40 (31 to 49) 100 42
Normothermia group     
   13 minutes 73 (68 to 78) 95 (92 to 98) 71 (66 to 76) 96 (94 to 98) 92
   15 minutes 85 (81 to 89) 94 (91 to 97) 69 (64 to 74) 98 (96 to 99) 93
   18 minutes 90 (87 to 93) 91 (88 to 94) 62 (56 to 68) 98 (96 to 99) 91
   20 minutes 92 (89 to 95) 88 (84 to 92) 55 (49 to 61) 99 (98 to 99) 89
   45 minutes 100 49 (43 to 55) 24 (19 to 29) 100 56
  1. Data presented as mean (95% confidence interval) (%). Time interval from collapse to return of spontaneous circulation (CPA-ROSC) cut-off value of 29 minutes in the hypothermia group and 15 minutes in the normothermia group had the highest combined sensitivity and specificity, with accuracies of 75.4% and 92.8%, respectively.