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Table 5 Clinical outcomes in the three intervention groups

From: Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial

 

CVP group

n= 45

SV group

n= 45

SV & DPX group

n= 45

P

Complications

(number of patients, %)

30 (67%)

26 (58%)

31 (69%)

0.51

Cardiac complications (number of patients, %)

4 (9%)

3 (7%)

3 (7%)

0.90

Infectious complications (number of patients, %)

29 (64%)

24 (53%)

28 (62%)

0.52

Other complications (number of patients, %)

10 (22%)

14 (31%)

12 (27%)

0.63

Acute kidney injury within 7 days of surgery

10 (22%)

3 (7%)

4 (9%)

0.055*

Critical care free days within 28 days of surgery

24 (21-26)

24 (21-26)

26 (21-27)

0.45

Duration of hospital stay (days)

15 (10-26)

14 (11-26)

16 (11-28)

0.73

Hospital mortality (%)

6 (13%)

5 (11%)

4 (9%)

0.45

  1. Data presented as median (interquartile range) or absolute values (%). Note: A number of patients developed more than one complication. Acute kidney injury at seven days not included in 28 day complication outcome.
  2. *Significant difference in incidence of acute kidney injury between pooled SV and SV & DPX groups and the CVP group (P = 0.03, post hoc analysis). CVP, central venous pressure; DPX, dopexamine; SV, stroke volume.