Table 2 Surgical, ICU, and outcome data of patients receiving aprotinin and tranexamic acid
| Â | Â | Aprotinin | Tranexamic acid | Â | ||
|---|---|---|---|---|---|---|
CABG | n | 349 | 231 | Â | ||
| Â | % in group | 63.1% | 69.0% | Â | ||
Valve | n | 106 | 48 | Â | ||
| Â | % in group | 19.2% | 14.3% | Â | ||
Double valve | n | 11 | 2 | Â | ||
| Â | % in group | 2.0% | 0.6% | Â | ||
CABG plus valve | n | 68 | 41 | Â | ||
| Â | % in group | 12.3% | 12.2% | Â | ||
Other | n | 19 | 13 | Â | ||
| Â | % in group | 3.4% | 3.9% | Â | ||
| Â | Â | Mean | SD | Mean | SD | P |
Duration of surgery (min) | Â | Â | Â | Â | Â | |
All patients | 206 | 60 | 211 | 71 | 0.28 | |
Open-heart procedures | 210 | 65 | 235 | 79 | < 0.01 | |
CPB time (min) | Â | Â | Â | Â | Â | |
All patients | 89 | 42 | 88 | 46 | 0.79 | |
Open-heart procedures | 104 | 47 | 114 | 53 | 0.07 | |
Cross-clamp time (min) | Â | Â | Â | Â | Â | |
All patients | 59 | 34 | 57 | 36 | 0.37 | |
Open-heart procedures | 77 | 40 | 85 | 43 | 0.08 | |
Euroscore II | Â | Â | Â | Â | Â | |
All patients | 6.3 | 3.9 | 5.8 | 3.7 | 0.08 | |
Open-heart procedures | 7.7 | 3.6 | 7.3 | 3.7 | 0.42 | |
ICU treatment (days) | Â | Â | Â | Â | Â | |
All patients | 3.1 | 9.5 | 3.5 | 8.1 | 0.51 | |
Open-heart procedures | 4.3 | 13.8 | 5.7 | 11.8 | 0.38 | |
Hospital stay (days) | Â | Â | Â | Â | Â | |
All patients | 17.0 | 17.1 | 18.9 | 18.6 | 0.11 | |
Open-heart procedures | 20.8 | 20.8 | 23.6 | 25.1 | 0.28 | |
Mechanical ventilation (h) | Â | Â | Â | Â | Â | |
All patients | 25.6 | 128.0 | 45.4 | 187.3 | 0.06 | |
Open-heart procedures | 36.3 | 188.4 | 83.0 | 263.6 | 0.07 | |
APACHE II (admission ICU) | Â | Â | Â | Â | Â | |
All patients | 19.4 | 6.8 | 19.3 | 7.0 | 0.89 | |
Open-heart procedures | 20.2 | 7.3 | 19.8 | 6.7 | 0.60 | |
SAPS II (admission ICU) | Â | Â | Â | Â | Â | |
All patients | 34.3 | 12.4 | 36.4 | 12.5 | 0.02 | |
Open-heart procedures | 36.7 | 13.0 | 39.7 | 13.1 | 0.06 | |