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Table 1 Functions of phosphate

From: Treatment of hypophosphatemia in the intensive care unit: a review

Form

Function

Hydroxyapatite

Bone structure

Phospholipids

Structure of cell membranes

Adenosine triphosphate (ATP) and creatine phosphate

Energy storage and metabolism

Nucleic acids and nucleoproteins

Genetic translation

Phosphorylation of proteins

Key regulatory mechanism; activation of enzymes, cell-signaling cascade

2,3-Diphosphoglycerate

Modulates oxygen release by hemoglobin

Inorganic phosphate

Acid-base buffer