Table 2 Hemodynamics, electrolytes, respiratory parameters lactate, ALT and Cystatin C levels and urine output of mechanically ventilated mice
From: Simvastatin attenuates ventilator-induced lung injury in mice
| Â | 6 h Vent. | 6 h Vent. + Simva | ||
|---|---|---|---|---|
| Â | mean | SD | mean | SD |
Na + (mmol/l) | 159 | 5 | 159 | 4 |
K + (mmol/l) | 4.7 | 0.5 | 4.7 | 0.4 |
Cl - (mmol/l) | 124 | 4 | 125 | 4 |
Ca 2+ (mmol/l) | 1.29 | 0.06 | 1.30 | 0.05 |
ph | 7.45 | 0.08 | 7.51 | 0.08 |
p a CO 2 (mmHg) | 42.2 | 4.8 | 34.5 | 10.0 |
SBE (mmol/l) | 3.0 | 2.1 | 3.5 | 1.7 |
HCO 3 - (mmol/l) | 26.7 | 2.6 | 26.6 | 2.7 |
Lactate (mmol/l) | 1.5 | 0.4 | 1.6 | 0.3 |
ALT (U/l) | 30 | 12 | 21 | 4 |
Cystatin C (ng/ml) | 443 | 64 | 479 | 65 |
MAP 0 h (mmHg) | 91 | 7 | 87 | 10 |
MAP 1 h (mmHg) | 74 | 7 | 72 | 7 |
MAP 2 h (mmHg) | 68 | 5 | 70 | 6 |
MAP 3 h (mmHg) | 70 | 6 | 70 | 7 |
MAP 4 h (mmHg) | 68 | 5 | 69 | 7 |
MAP 5 h (mmHg) | 69 | 6 | 67 | 7 |
MAP 6 h (mmHg) | 73 | 8 | 72 | 10 |
Urine Output 6 h (μl) | 908 | 294 | 669 | 207 |