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Table 6 Hemodynamic variables in the subgroups of patients with left ventricular ejection fraction ≤45% and an achieved mean arterial pressure inferior (n = 17) or superior (n = 17) to the median value (74 mm Hg)

From: Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension

  Achieved MAP < 75 mm Hg Achieved MAP ≥75 mm Hg
  Before NE
(introduction/increase)
After NE
(introduction/increase)
Before NE
(introduction/increase)
After NE
(introduction/increase)
Heart rate, beats/min 100 ± 16 96 ± 17 92 ± 18 91 ± 17
MAP, mm Hg 49 ± 8 68 ± 4a 58 ± 8 82 ± 7a
DAP, mm Hg 36 ± 6 48 ± 7a 40 ± 8 56 ± 9a
CI, L/min/m2 2.7 ± 0.9 3.0 ± 1.0a 3.2 ± 0.8 3.4 ± 0.8
SVI, ml/m2 28 ± 11 33 ± 13a 35 ± 10 38 ± 10
GEDVI, ml/m2 660 ± 167 770 ± 185a 737 ± 157 766 ± 201
CFI, per min 3.9 ± 1.5 4.0 ± 1.5 4.4 ± 1.2 4.6 ± 1.4
SVRI, dynes/sec/cm5/m2 1,654 ± 639 1,993 ± 709a 1,523 ± 355 2,057 ± 527a
  1. CFI, cardiac function index; CI, cardiac index; DAP, diastolic arterial pressure; GEDVI, global end-diastolic volume index; HR, heart rate; MAP, mean arterial pressure; NE, norepinephrine; SVI, stroke volume index; SVRI, index of systemic vascular resistance.
  2. aP < 0.05 vs. before norepinephrine.