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Table 5 Hemodynamic variables in the subgroups of patients with left ventricular ejection fraction >45% and an achieved mean arterial pressure either inferior (n = 36) or superior (n = 35) to the median value (75 mm Hg)

From: Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension

  Achieved MAP <75 mm Hg Achieved MAP ≥75 mm Hg
  Before NE
(introduction/increase)
After NE
(introduction/increase)
Before NE
(introduction/increase)
After NE
(introduction/increase)
Heart rate, beats/min 105 ± 22 104 ± 21 93 ± 23 95 ± 21
MAP, mm Hg 52 ± 7 69 ± 5a 56 ± 6 83 ± 6a
DAP, mm Hg 37 ± 7 48 ± 7a 39 ± 4 56 ± 8a
CI, L/min/m2 3.2 ± 1.1 3.6 ± 1.1a 3.5 ± 1.1 4.1 ± 1.3a
SVI, ml/m2 32 ± 13 36 ± 13a 40 ± 12 46 ± 15a
GEDVI, ml/m2 674 ± 133 731 ± 157a 687 ± 147 729 ± 160a
CFI, per min 4.8 ± 1.7 5.0 ± 1.6 5.3 ± 1.7 5.8 ± 1.7a
SVRI, dynes/sec/cm5/m2 1,435 ± 487 1,639 ± 486a 1,405 ± 503 1,725 ± 577a
  1. CFI, cardiac function index; CI, cardiac index; DAP, diastolic arterial pressure; GEDVI, global end-diastolic volume index; HR, heart rate; MAP, mean arterial pressure; NE, norepinephrine; SVI, stroke volume index; SVRI, index of systemic vascular resistance.
  2. aP < 0.05 vs. before norepinephrine.