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Table 2 Hemodynamic variables before and after introduction of norepinephrine (or increase in its dose) in the whole population (n = 105)

From: Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension

 

Before norepinephrine

(introduction/increase)

After norepinephrine

(introduction/increase)

Heart rate, beats/min

98 ± 21

97 ± 19

MAP, mm Hg

54 ± 8

76 ± 9a

DAP, mm Hg

38 ± 6

52 ± 8a

CI, L/min/m2

3.2 ± 1.0

3.6 ± 1.1a

SVI, ml/m2

34 ± 12

39 ± 13a

GEDVI, ml/m2

694 ± 148

742 ± 168a

CFI, per minute

4.7 ± 1.5

5.0 ± 1.6a

SVRI, dynes/sec/cm5/m2

1,471 ± 481

1,822 ± 502a

  1. CFI, cardiac function index; CI, cardiac index; DAP, diastolic arterial pressure; GEDVI, global end-diastolic volume index; HR, heart rate; MAP, mean arterial pressure; SVI, stroke volume index; SVRI, index of systemic vascular resistance.
  2. aP < 0.05 vs. before norepinephrine.