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Table 1 Baseline characteristics of the two validation cohorts

From: Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials

  Mayo n= 109 ARDS-net n= 1,896
Age in years, median (IQR) 62 (50-72) 50 (38-64)
Female gender, n (%) 56 (51.4) 845 (44.6)
Predicted hospital death, median (IQR) 0.43 (0.19-0.70) 0.31 (0.14-0.58)
PaO2/FiO2 day 1, median (IQR) 118 (82.5-164) 145 (108-195)
PaO2/FiO2 day 3, median (IQR) 175 (117, 241) 155 (114.5-207)
Tidal volume (ml) day 1, median (IQR) 420 (360-500) 420 (350-500)
PEEP (mmH20) day 1, median (IQR) 8 (5-12) 10 (8-14)
Estimated dead-space (%) day 1, median (IQR) 72.5 (64-78.7) 66.3 (57.5-73.6)
Estimated dead-space (%) day 3, median (IQR) 70.8 (61.2-76.3) 68.2 (59.6-75.1)
Hospital mortality n (%) 37 (34) 560 (29.5)
Duration of mechanical ventilation median (IQR) (days) 6 (3-11) 10.5 (6-19)
  1. ARDS-net, acute respiratory distress syndrome-network; FiO2, fraction of inspired oxygen; IQR, interquartile range; PaO2, partial pressureof arterial pressure; PEEP, positive end-expiratory pressure.