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Table 1 Baseline clinical characteristics of the patients

From: Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury

Variables

Control

Surfactant

P value

 

(n = 10)

(n = 10)

 

Male/female

9/1

8/2

NS

Age (years)

59 ± 16

62 ± 12

NS

SAPS II

40 ± 10

41 ± 10

NS

LISS

2.3 ± 0.4

2.6 ± 0.5

NS

Septic shock (%)

80%

70%

NS

Survival (%)

70%

70%

NS

Cause of ALI/ARDS

   

   Bronchopneumonia

4

6

 

   Aspiration pneumonia

1

1

NS

   Lung contusion

2

0

 

   Sepsis

3

3

 

PaCO2 (mmHg)

38.4 ± 8.2

37.9 ± 7

NS

PaO2/FiO2 (mmHg)

200 ± 63

201 ± 64

NS

TV/kg (ml)

5.7 ± 0.8

6 ± 0.9

NS

RR (breaths/min)

23 ± 4

20 ± 6

NS

Ppeak (cmH2O)

32 ± 5

32 ± 6

NS

Pplat (cmH2O)

23 ± 4

23 ± 5

NS

PEEP (cmH2O)

9.7 ± 0.9

9.4 ± 1

NS

Crs (ml.cmH2O-1)

38 ± 12

41 ± 23

NS

HR (beats/min)

110 ± 23

88 ± 24

NS

MAP (mmHg)

86 ± 15

87 ± 20

NS

  1. ALI, acute lung injury; ARDS, acute respiratory distress syndrome; Crs, compliance of respiratory system; FiO2, fraction of inspired oxygen; HR, heart rate; LISS, lung injury severity score; MAP, mean arterial pressure; NS, not significant; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen; Ppeak, peak airway pressure; PEEP, positive end-expiratory pressure; Pplat, plateau airway pressure; RR, respiratory rate; SAPS II, simplified acute physiology score II; Surfactant, porcine-derived lung surfactant; TV, tidal volume.
  2. Data are expressed as mean ± standard deviation.
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