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Table 1 Baseline clinical characteristics of the patients

From: Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury

Variables Control Surfactant P value
  (n = 10) (n = 10)  
Male/female 9/1 8/2 NS
Age (years) 59 ± 16 62 ± 12 NS
SAPS II 40 ± 10 41 ± 10 NS
LISS 2.3 ± 0.4 2.6 ± 0.5 NS
Septic shock (%) 80% 70% NS
Survival (%) 70% 70% NS
Cause of ALI/ARDS    
   Bronchopneumonia 4 6  
   Aspiration pneumonia 1 1 NS
   Lung contusion 2 0  
   Sepsis 3 3  
PaCO2 (mmHg) 38.4 ± 8.2 37.9 ± 7 NS
PaO2/FiO2 (mmHg) 200 ± 63 201 ± 64 NS
TV/kg (ml) 5.7 ± 0.8 6 ± 0.9 NS
RR (breaths/min) 23 ± 4 20 ± 6 NS
Ppeak (cmH2O) 32 ± 5 32 ± 6 NS
Pplat (cmH2O) 23 ± 4 23 ± 5 NS
PEEP (cmH2O) 9.7 ± 0.9 9.4 ± 1 NS
Crs (ml.cmH2O-1) 38 ± 12 41 ± 23 NS
HR (beats/min) 110 ± 23 88 ± 24 NS
MAP (mmHg) 86 ± 15 87 ± 20 NS
  1. ALI, acute lung injury; ARDS, acute respiratory distress syndrome; Crs, compliance of respiratory system; FiO2, fraction of inspired oxygen; HR, heart rate; LISS, lung injury severity score; MAP, mean arterial pressure; NS, not significant; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen; Ppeak, peak airway pressure; PEEP, positive end-expiratory pressure; Pplat, plateau airway pressure; RR, respiratory rate; SAPS II, simplified acute physiology score II; Surfactant, porcine-derived lung surfactant; TV, tidal volume.
  2. Data are expressed as mean ± standard deviation.