|
Healthy controls
|
Septic shock patients
|
---|
| |
Days 1 to 2
|
Days 3 to 5
|
---|
Leukocytes
|
5658 (4,954 to 6,146)
|
14,673 (9,562 to 18,446)
|
15,390* (10,097 to 25,235)
|
Lymphocytes
|
1549 (1,295 to 1,831)
|
701* (432 to 1,531)
|
1,110 (634 to 1,482)
|
T cells
|
1090 (902 to 1,470)
|
421* (209 to 547)
|
529 (335 to 1,031)
|
CD4+ T lymphocytes
|
890 (569 to 1,141)
|
220* (115 to 354)
|
479 (218 to 827)
|
CD8+ T lymphocytes
|
320 (228 to 349)
|
155* (36 to 207)
|
158 (70 to 304)
|
- Results expressed as the median (interquartile range, Q1 to Q3) number of cells/μl. Blood samples were obtained from 13 septic shock patients at days 1 to 2 and at days 3 to 5 after diagnosis of shock. Circulating leukocyte immunophenotyping was systematically performed by flow cytometry. The following leukocyte subsets were analyzed: total number of leukocytes, total number of lymphocytes, T cells (CD45+CD3+), and CD4+ (CD45+CD4+CD3+) and CD8+ (CD45+CD8+CD3+) T-lymphocyte subpopulations. Comparison versus healthy volunteers values (mean) performed using the Mann-Whitney U test with correction for the number of tests performed: *P < 0.025.