Figure 4
From: Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients
Gene expression of pro-apoptotic Bcl-2 family members and death receptor FAS measured by qRT-PCR. mRNA expressions of pro-apoptotic genes (a) BAX, (b) BAK, (c) BID, (d) BIM and (e) FAS were quantified by quantitative reverse-transcription PCR in healthy volunteers (HV) (open boxes, n = 11) and septic shock patients (grey boxes) at days 1 to 2 (D1-2, n = 6) and days 3 to 5 (D3-5, n = 8). The targeted genes mRNA levels were normalized to that of the housekeeping gene peptidylpropyl isomerase B. Data presented as boxplots. Comparison versus healthy volunteers values (mean) performed using the Mann-Whitney U test (*P < 0.025).