Skip to main content

Table 1 Results from analyses of samples

From: Clinical effects of adsorption of lipopolysaccharide in the treatment of Gram-negative severe sepsis

 

Stage

 

I

II

III

IV

Parameter

RefG

AdG

RefG

Adg

REfG

Adg

RefG

AdG

LPS (EU/ml)

1.4 ± 0.0

1.4 ± 0.0

1.4 ± 0.2

0.8 ± 0.2

1.4 ± 0.6

0.4 ± 0.3

1.4 ± 0.2

0.2 ± 0.0

PCT (ng/ml)

15.6 ± 2.8

16.0 ± 2.5

16.4 ± 2.2

11.6 ± 3.7

14.3 ± 2.8

4.2 ± 2.2

13.6 ± 3.8

1.4 ± 0.9

CI (l/min/m2)

2.7 ± 0.8

2.9 ± 0.7

2.9 ± 0.8

3.9 ± 0.9

3.1 ± 0.6

3.0 ± 0.7

2.9 ± 0.5

4.7 ± 1.9

MAP (mmHg)

60.6 ± 4.3

59.1 ± 5.8

66.9 ± 5.5

79.7 ± 4.6

69.4 ± 1.4

81.1 ± 2.9

69.1 ± 3.2

83.8 ± 5.7

Pa2 (mmHg)

88.2 ± 2.1

84.5 ± 12.1

89.9 ± 14.4

108.7 ± 16.1

88.3 ± 9.4

129.4 ± 12.2

91.7 ± 7.8

130.6 ± 9.2

FlO2 (%)

60.0 ± 0.0

50.0 ± 4.1

50.0 ± 0.0

40.1 ± 4.3

50.0 ± 0.0

37.4 ± 3.5

50.0 ± 0.0

35.0 ± 0.0

ELWl (ml/kg)

12.9 ± 3.3

13.2 ± 1.2

13.1 ± 2.2

9.2 ± 3.1

11.0 ± 2.7

7.1 ± 1.1

9.7 ± 2.1

4.3 ± 2.1

PAO2/FiO2

146.4 ± 12.1

168.4 ± 16.5

179.2 ± 10.1

270.1 ± 24.3

176.3 ± 9.5

345.0 ± 21.1

183.2 ± 12.1

373.5 ± 14.3

Dopamin (μg/kg/min)

12.0 ± 1.7

13.3 ± 3.9

14.2 ± 2.2

8.1 ± 2.1

13.5 ± 3.1

3.3 ± 1.4

11.7 ± 1.9

3.1 ± 0.3

SaO2 (%)

87.3 ± 2.2

86.7 ± 3.1

86.9 ± 1.9

94.9 ± 2.8

89.5 ± 3.5

98.2 ± 0.9

93.6 ± 5.4

98.5 ± 0.4

SVO2 venous (%)

79.8 ± 2.5

80.0 ± 1.5

82.2 ± 2.3

76.0 ± 3.4

85.3 ± 3.1

71.3 ± 2.4

79.8 ± 2.9

72.8 ± 3.7

Lactate (mol/l)

4.9 ± 2.1

4.8 ± 1.7

5.5 ± 1.3

3.2 ± 1.1

5.3 ± 1.3

2.4 ± 0.9

5.4 ± 0.9

1.7 ± 0.6

APTt (sec)

41.5 ± 5.9

42.1 ± 4.6

46.6 ± 7.7

58.4 ± 5.7

48.8 ± 12.1

66.3 ± 8.5

50.2 ± 11.8

62.3 ± 3.4

  1. I, baseline, prior to first adsorber treatment; II, prior to second adsorber treatment/day after first treatment; III, 2 days after second adsorber treatment/3 days after first adsorber treatment.