| 2 h post-extubation | 4 h post-extubation | 6 h post-extubation |  | |||
---|---|---|---|---|---|---|---|
 | Dexmed. | Placebo | Dexmed. | Placebo | Dexmed. | Placebo | P value |
Resp. rate | 18.0(4.6) | 20.4(6.1) | 16.6(1.5) | 20.1(5.2) | 16.8(2.8) | 19.5(4.5) | 0.05 |
PaCO2 | 5.4(0.7) | 5.5(0.9) | 5.8(1.0) | 5.6(0.6) | 5.4(0.6) | 5.3(0.8) | NS |
pH | 7.4(0.1) | 7.3(0.1) | 7.3(0.1) | 7.3(0.1) | 7.4(0.1) | 7.4(0.1) | NS |
PaO2/FiO2 | 38.4(16.5) | 30.0(10.3) | 39.5(13.3) | 29.2(7.2) | 43.0(13.2) | 29.0(8.0) | 0.02 |