Skip to main content

Table 4 Different models of logistic regression to predict sepsis diagnosis on admission * (n = 74 patients)

From: Proven infection-related sepsis induces a differential stress response early after ICU admission

  AUC (95% CI) OR (95% CI) P-value
Model 1 (M1)    
   ACTH ≤ 233 nM/L 0.875 (0.774 to 0.942) 9.192 (2.466 to 34.265) 0.001
   Cortisol baseline ≥ 450 nM/L   4.279 (1.007 to 18.181) 0.049
   Sepsis score >7   5.371 (1.567 to 18.404) 0.007
Model 2 (M2)    
   ACTH ≤ 233 nM/L 0.903 (0.808 to 0.960) 21.16 (4.252 to 105.307) 0.0002
   Cortisol baseline ≥ 450 nM/L   8.81 (1.616 to 48.037) 0.012
   Procalcitonin (PCT) >2 ng/mL   28.558 (4.393 to 185.636) 0.0004
Model 3 (M3)    
   ACTH ≤ 233 nM/L 0.805 (0.693 to 0.890) 9.125 (2.667 to 31.218) 0.0004
   Cortisol baseline ≥ 450 nM/L   7.457 (1.89 to 29.426) 0.004
Model 4 (M4)    
   Procalcitonin (PCT) >2 ng/mL 0.726 (0.607 to 0.826) 16.889 (3.523 to 80.959) 0.0004
Model 5 (M5)    
   Sepsis score >7 0.727 (0.607 to 0.827) 6.481 (2.34 to 17.952) 0.0003
  1. ACTH, adreno corticotropic hormone; AUC, area under the receiver operating characteristic curve; CI, confidence interval; OR: odds ratio; PCT, procalcitonin.