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Table 1 Specifications of neuropeptide/protein blood dosages

From: Proven infection-related sepsis induces a differential stress response early after ICU admission

Protein/Peptide

Extraction

Assay

Source

Sensitivity

Range

Cortisol

None

ADVIA Centaur system

Siemens Medical Solutions Diagnostics, Tarrytown, NY, USA.

5.5 to 2069 nMol/L

85 to 618 nMol/L

ACTH

None

ImmuChemTM 125I RIA kit

MP Biomedicals, LLC, Diagnostics Division, Orangeburg, NY, USA.

5.7 pg/mL

0 to 1000 pg/mL

Apelin

C-18 SEP-column and lyophilisation

Apelin-12 enzyme immunoassay kit

Phoenix Pharmaceuticals Inc, Burlingame, California, USA.

0.07 ng/mL

0 to 100 ng/mL

Arg Vasopressin (AVP)

Acetone and ether procedure

Arg8-Vasopressin enzyme Immunoassay kit

Assay Designs, Ann Arbor, MI, USA.

3.39 pg/mL

3.39 to 1,000 pg/mL

Copeptin

C-18 SEP-column and lyophilisation

Copeptin enzyme immunoassay kit

R&D Systems, Minneapolis, Minnesota, USA.

18 pg/mL

0 to 1,000 pg/mL

SDF-1α

Centrifuged for complete platelet removal

SDF-1α enzyme immunoassay

R&D Systems, Minneapolis, Minnesota, USA.

18 pg/mL

0 to 10,000 pg/mL

Procalcitonin (PCT)

None

Immunoluminometric

PCT LIA B.R.A.H.M.S Diag

LLC, Georgia, USA

0.3 ng/mL

0.3 to 500 ng/mL

  1. ACTH, adreno corticotropic hormone. AVP, arginine vasopressin. SDF-1α, stromal-derived factor-1 alpha. PCT, procalcitonin.