Figure 2From: Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsisIf an antioxidant is attached to triphenylphosphonium, it accumulates several hundred-fold within mitochondria in cells and selectively blocks mitochondrial oxidative damage and mitochondrial redox signaling. Targeted antioxidants include derivatives of the endogenous antioxidants ubiquinol (MitoQ) and α-tocopherol (MitoVitE).Back to article page