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Table 3 Area under the curve (AUC 0-4) for plasma ibuprofen concentrations

From: A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults

Average of treatment Group

100 mg IV Ibuprofen

200 mg IV Ibuprofen

400 mg IV Ibuprofen

AUC0-4 (μg.h/mL)

22.33 +/- 12.75 (SD)

32.62 +/- 17.39 (SD)

70.64 +/- 31.93 (SD)

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Critical Care

ISSN: 1364-8535