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Table 4 Biochemical variables

From: Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized study

Variable

Baseline

End of surgery

4 hours postOP

8 hours postOP

24 hours postOP

ANOVA on rpt.m.

Serum lactate (mmol/l)

Vigileo

1.48 ± 0.44

1.78 ± 0.83 #

1.75 ± 0.86

1.85 ± 0.98

1.25 ± 0.52

0.002

Control

1.42 ± 0.43

2.25 ± 1.12***

2.14 ± 1.11***

2.10 ± 1.18**

1.4 ± 0.50

< 0.001

Arterial pH

Vigileo

7.43 ± 0.03

7.37 ± 0.05*** #

7.39 ± 0.04**

7.41 ± 0.05

7.41 ± 0.03*

< 0.001

Control

7.41 ± 0.04

7.35 ± 0.05***

7.38 ± 0.05**

7.40 ± 0.05

7.42 ± 0.04

< 0.001

Base excess (mmol/l)

Vigileo

0.67 ± 1.72

-1.55 ± 1.91***

-0.23 ± 2.19*

0.41 ± 1.8

1.36 ± 2.36

< 0.001

Control

-0.19 ± 2.55

-2.15 ± 2.54***

-0.55 ± 2.44

-0.09 ± 2.64

1.17 ± 2.17

< 0.001

Serum bicarbonate (mmol/l)

Vigileo

24.63 ± 1.81

23.05 ± 1.68***

24.11 ± 2.36

24.65 ± 1.84

25.59 ± 2.59

< 0.001

Control

23.81 ± 2.69

22.67 ± 2.16**

24.04 ± 2.28

24.33 ± 2.57

25.45 ± 2.94

< 0.001

ScvO2 (%)

Vigileo

71.79 ± 6.94

80.18 ± 7.86***

69.43 ± 8.40

68.54 ± 8.23

67.61 ± 6.54*

< 0.001

Control

72.27 ± 6.77

80.04 ± 6.87*

69.00 ± 7.92

69.50 ± 7.84

67.36 ± 7.14**

< 0.001

Hemoglobin (g/dl)

Vigileo

12.3 ± 1.5

10.5 ± 1.1***

11.4 ± 1.5***

11.2 ± 1.5***

10.7 ± 1.3***

< 0.001

Control

12.7 ± 1.6

10.4 ± 1.2***

11.4 ± 1.3***

11.2 ± 1.4***

10.8 ± 1.0***

< 0.001

  1. Perioperative period analyzed only for patients whose intraoperative protocol was carried in full extent; *P < 0.05 **P < 0.01 ***P < 0.001 analysis of variance (ANOVA) on repeated measurements with Bonferroni correction against baseline; #P< 0.05 Vigileo vs. Control (t-test); Values are presented as mean ± standard deviation.
  2. PostOP, postoperatively; ScvO2, central venous oxygen saturation.