Skip to main content

Table 4 Biochemical variables

From: Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized study

Variable Baseline End of surgery 4 hours postOP 8 hours postOP 24 hours postOP ANOVA on rpt.m.
Serum lactate (mmol/l)
Vigileo 1.48 ± 0.44 1.78 ± 0.83 # 1.75 ± 0.86 1.85 ± 0.98 1.25 ± 0.52 0.002
Control 1.42 ± 0.43 2.25 ± 1.12*** 2.14 ± 1.11*** 2.10 ± 1.18** 1.4 ± 0.50 < 0.001
Arterial pH
Vigileo 7.43 ± 0.03 7.37 ± 0.05*** # 7.39 ± 0.04** 7.41 ± 0.05 7.41 ± 0.03* < 0.001
Control 7.41 ± 0.04 7.35 ± 0.05*** 7.38 ± 0.05** 7.40 ± 0.05 7.42 ± 0.04 < 0.001
Base excess (mmol/l)
Vigileo 0.67 ± 1.72 -1.55 ± 1.91*** -0.23 ± 2.19* 0.41 ± 1.8 1.36 ± 2.36 < 0.001
Control -0.19 ± 2.55 -2.15 ± 2.54*** -0.55 ± 2.44 -0.09 ± 2.64 1.17 ± 2.17 < 0.001
Serum bicarbonate (mmol/l)
Vigileo 24.63 ± 1.81 23.05 ± 1.68*** 24.11 ± 2.36 24.65 ± 1.84 25.59 ± 2.59 < 0.001
Control 23.81 ± 2.69 22.67 ± 2.16** 24.04 ± 2.28 24.33 ± 2.57 25.45 ± 2.94 < 0.001
ScvO2 (%)
Vigileo 71.79 ± 6.94 80.18 ± 7.86*** 69.43 ± 8.40 68.54 ± 8.23 67.61 ± 6.54* < 0.001
Control 72.27 ± 6.77 80.04 ± 6.87* 69.00 ± 7.92 69.50 ± 7.84 67.36 ± 7.14** < 0.001
Hemoglobin (g/dl)
Vigileo 12.3 ± 1.5 10.5 ± 1.1*** 11.4 ± 1.5*** 11.2 ± 1.5*** 10.7 ± 1.3*** < 0.001
Control 12.7 ± 1.6 10.4 ± 1.2*** 11.4 ± 1.3*** 11.2 ± 1.4*** 10.8 ± 1.0*** < 0.001
  1. Perioperative period analyzed only for patients whose intraoperative protocol was carried in full extent; *P < 0.05 **P < 0.01 ***P < 0.001 analysis of variance (ANOVA) on repeated measurements with Bonferroni correction against baseline; #P< 0.05 Vigileo vs. Control (t-test); Values are presented as mean ± standard deviation.
  2. PostOP, postoperatively; ScvO2, central venous oxygen saturation.