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Table 2 Echocardiographic data

From: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury

  

HYPO

NORMO

HYPER

  

NR

RM-CPAP

NR

RM-CPAP

NR

RM-CPAP

Cardiac

Output (ml.min-1)

BASELINE

20 ± 10

20 ± 10

20 ± 10

20 ± 10

20 ± 10

40 ± 10†§

 

END

10 ± 10

10 ± 10

10 ± 10

20 ± 10

60 ± 10* **#

60 ± 10‡§

Stroke volume (ml)

BASELINE

0.17 ± 0.01

0.13 ± 0.01†

0.13 ± 0.01**

0.13 ± 0.01

0.10 ± 0.05**

0.13 ± 0.01

 

END

0.10 ± 0.01*

0.10 ± 0.01

0.10 ± 0.01

0.13 ± 0.01

0.33 ± 0.01**#

0.26 ± 0.01*†‡§

Ejection

fraction (%)

BASELINE

74 ± 1

73 ± 3

78 ± 4

74 ± 4

74 ± 1

68 ± 7

 

END

63 ± 4*

65 ± 1*

71 ± 1

73 ± 1‡

86 ± 3* **#

88 ± 3*‡§

  1. Echocardiographic data measured at BASELINE and after one hour of mechanical ventilation (END). Animals were randomly assigned to hypovolemia (HYPO), normovolemia (NORMO) or hypervolemia (HYPER) with recruitment maneuver (RM-CPAP) or not (NR). Values are mean ± standard error of the mean of six rats in each group. *Significantly different from BASELINE (P < 0.05). †Significantly different from NR (P < 0.05). **Significantly different from HYPO-NR (P < 0.05). ‡Significantly different from HYPO-RM-CPAP (P < 0.05). #Significantly different from NORMO-NR (P < 0.05). §Significantly different from NORMO-RM-CPAP (P < 0.05).
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Critical Care

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