Skip to main content

Table 1 Mean arterial pressure and inferior vena cava and right atrium dimensions

From: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury

    BASELINE 5 min 10 min 15 min 20 min 80 min
MAP (mmHg) HYPO NR 110 ± 6 107 ± 5 77 ± 4* 70 ± 3* 67 ± 3* 62 ± 3*
   RM-CPAP 110 ± 2 97 ± 2 76 ± 2* 71 ± 1* 65 ± 2* 63 ± 1*
  NORMO NR 104 ± 8 101 ± 6 100 ± 6** 103 ± 6** 100 ± 4** 97 ± 4**
   RM-CPAP 103 ± 2 103 ± 2 100 ± 2‡ 105 ± 3‡ 96 ± 3‡ 95 ± 2‡
  HYPER NR 106 ± 3 128 ± 2* **# 130 ± 2* **# 131 ± 3* **# 131 ± 2* **# 126 ± 2* **#
   RM-CPAP 103 ± 2 126 ± 5*‡§ 129 ± 4*‡§ 128 ± 4*‡§ 124 ± 2*‡§ 117 ± 5*‡§
IVC
(mm)
HYPO NR 1.6 ± 0.2 1.5 ± 0.1 1.2 ± 0.1* 1.0 ± 0.1* 1.0 ± 0.1* 0.9 ± 0.0*
   RM-CPAP 1.6 ± 0.2 1.4 ± 0.1 1.1 ± 0.1* 0.9 ± 0.1* 0.8 ± 0.0* 0.7 ± 0.0*
  NORMO NR 1.6 ± 0.1 1.7 ± 0.1 1.6 ± 0.1 1.7 ± 0.0** 1.7 ± 0.0** 1.5 ± 0.0**
   RM-CPAP 1.5 ± 0.0 1.5 ± 0.0 1.4 ± 0.0 1.6 ± 0.0‡ 1.6 ± 0.0‡ 1.4 ± 0.0‡
  HYPER NR 1.4 ± 0.0 2.3 ± 0.2* **# 2.6 ± 0.1* **# 2.5 ± 0.3* **# 2.6 ± 0.3* **# 2.6 ± 0.1* **#
   RM-CPAP 1.4 ± 0.0 2.1 ± 0.2* ‡§ 2.5 ± 0.1* ‡§ 2.6 ± 0.1* ‡§ 2.6 ± 0.2* ‡§ 2.4 ± 0.2* ‡§
RA
(mm)
HYPO NR 4.0 ± 0.4 3.9 ± 0.6 3.8 ± 0.4 2.8 ± 0.2* 2.3 ± 0.3* 2.7 ± 0.2*
   RM-CPAP 4.2 ± 0.1 3.4 ± 0.1 3.1 ± 0.0* 2.9 ± 0.0* 2.5 ± 0.2* 3.0 ± 0.0*
  NORMO NR 3.5 ± 0.0 3.5 ± 0.0 3.7 ± 0.0 3.5 ± 0.0** 3.6 ± 0.0** 3.3 ± 0.0**
   RM-CPAP 3.6 ± 0.1 3.5 ± 0.1 3.6 ± 0.0 3.5 ± 0.0‡ 3.6 ± 0.0‡ 3.5 ± 0.1‡
  HYPER NR 3.9 ± 0.1 4.8 ± 0.5 6.1 ± 0.4* **# 6.5 ± 0.4* **# 7.1 ± 0.4* **# 7.4 ± 0.0* **#
   RM-CPAP 4.1 ± 0.1 6.5 ± 0.5*‡§ 7.2 ± 0.3*‡§ 7.2 ± 0.3*‡§ 7.3 ± 0.3*‡§ 7.1 ± 0.2*‡§
  1. Mean arterial pressure (MAP), and inferior vena cava (IVC) and right atrium (RA) dimensions at BASELINE, during the induction of hyper or hypovolemia (BASELINE until 20 min), and at the end of the experiment (80 min). Animals were randomly assigned to hypovolemia (HYPO), normovolemia (NORMO) or hypervolemia (HYPER) with recruitment maneuver (RM-CPAP) or not (NR). Values are shown as mean ± standard error of the mean of six rats in each group. *Significantly different from BASELINE (P < 0.05). †Significantly different from NR (P <0.05). **Significantly different from HYPO-NR (P < 0.05). ‡ Significantly different from HYPO-RM-CPAP (P < 0.05). #Significantly different from NORMO-NR (P < 0.05). §Significantly different from NORMO-RM-CPAP (P < 0.05).