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Table 1 Mean arterial pressure and inferior vena cava and right atrium dimensions

From: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury

   

BASELINE

5 min

10 min

15 min

20 min

80 min

MAP (mmHg)

HYPO

NR

110 ± 6

107 ± 5

77 ± 4*

70 ± 3*

67 ± 3*

62 ± 3*

  

RM-CPAP

110 ± 2

97 ± 2

76 ± 2*

71 ± 1*

65 ± 2*

63 ± 1*

 

NORMO

NR

104 ± 8

101 ± 6

100 ± 6**

103 ± 6**

100 ± 4**

97 ± 4**

  

RM-CPAP

103 ± 2

103 ± 2

100 ± 2‡

105 ± 3‡

96 ± 3‡

95 ± 2‡

 

HYPER

NR

106 ± 3

128 ± 2* **#

130 ± 2* **#

131 ± 3* **#

131 ± 2* **#

126 ± 2* **#

  

RM-CPAP

103 ± 2

126 ± 5*‡§

129 ± 4*‡§

128 ± 4*‡§

124 ± 2*‡§

117 ± 5*‡§

IVC

(mm)

HYPO

NR

1.6 ± 0.2

1.5 ± 0.1

1.2 ± 0.1*

1.0 ± 0.1*

1.0 ± 0.1*

0.9 ± 0.0*

  

RM-CPAP

1.6 ± 0.2

1.4 ± 0.1

1.1 ± 0.1*

0.9 ± 0.1*

0.8 ± 0.0*

0.7 ± 0.0*

 

NORMO

NR

1.6 ± 0.1

1.7 ± 0.1

1.6 ± 0.1

1.7 ± 0.0**

1.7 ± 0.0**

1.5 ± 0.0**

  

RM-CPAP

1.5 ± 0.0

1.5 ± 0.0

1.4 ± 0.0

1.6 ± 0.0‡

1.6 ± 0.0‡

1.4 ± 0.0‡

 

HYPER

NR

1.4 ± 0.0

2.3 ± 0.2* **#

2.6 ± 0.1* **#

2.5 ± 0.3* **#

2.6 ± 0.3* **#

2.6 ± 0.1* **#

  

RM-CPAP

1.4 ± 0.0

2.1 ± 0.2* ‡§

2.5 ± 0.1* ‡§

2.6 ± 0.1* ‡§

2.6 ± 0.2* ‡§

2.4 ± 0.2* ‡§

RA

(mm)

HYPO

NR

4.0 ± 0.4

3.9 ± 0.6

3.8 ± 0.4

2.8 ± 0.2*

2.3 ± 0.3*

2.7 ± 0.2*

  

RM-CPAP

4.2 ± 0.1

3.4 ± 0.1

3.1 ± 0.0*

2.9 ± 0.0*

2.5 ± 0.2*

3.0 ± 0.0*

 

NORMO

NR

3.5 ± 0.0

3.5 ± 0.0

3.7 ± 0.0

3.5 ± 0.0**

3.6 ± 0.0**

3.3 ± 0.0**

  

RM-CPAP

3.6 ± 0.1

3.5 ± 0.1

3.6 ± 0.0

3.5 ± 0.0‡

3.6 ± 0.0‡

3.5 ± 0.1‡

 

HYPER

NR

3.9 ± 0.1

4.8 ± 0.5

6.1 ± 0.4* **#

6.5 ± 0.4* **#

7.1 ± 0.4* **#

7.4 ± 0.0* **#

  

RM-CPAP

4.1 ± 0.1

6.5 ± 0.5*‡§

7.2 ± 0.3*‡§

7.2 ± 0.3*‡§

7.3 ± 0.3*‡§

7.1 ± 0.2*‡§

  1. Mean arterial pressure (MAP), and inferior vena cava (IVC) and right atrium (RA) dimensions at BASELINE, during the induction of hyper or hypovolemia (BASELINE until 20 min), and at the end of the experiment (80 min). Animals were randomly assigned to hypovolemia (HYPO), normovolemia (NORMO) or hypervolemia (HYPER) with recruitment maneuver (RM-CPAP) or not (NR). Values are shown as mean ± standard error of the mean of six rats in each group. *Significantly different from BASELINE (P < 0.05). †Significantly different from NR (P <0.05). **Significantly different from HYPO-NR (P < 0.05). ‡ Significantly different from HYPO-RM-CPAP (P < 0.05). #Significantly different from NORMO-NR (P < 0.05). §Significantly different from NORMO-RM-CPAP (P < 0.05).