TY - JOUR AU - Silva, Pedro L. AU - Cruz, Fernanda F. AU - Fujisaki, Livia C. AU - Oliveira, Gisele P. AU - Samary, Cynthia S. AU - Ornellas, Debora S. AU - Maron-Gutierrez, Tatiana AU - Rocha, Nazareth N. AU - Goldenberg, Regina AU - Garcia, Cristiane SNB AU - Morales, Marcelo M. AU - Capelozzi, Vera L. AU - Gama de Abreu, Marcelo AU - Pelosi, Paolo AU - Rocco, Patricia RM PY - 2010 DA - 2010/06/14 TI - Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury JO - Critical Care SP - R114 VL - 14 IS - 3 AB - Recruitment maneuvers (RMs) seem to be more effective in extrapulmonary acute lung injury (ALI), caused mainly by sepsis, than in pulmonary ALI. Nevertheless, the maintenance of adequate volemic status is particularly challenging in sepsis. Since the interaction between volemic status and RMs is not well established, we investigated the effects of RMs on lung and distal organs in the presence of hypovolemia, normovolemia, and hypervolemia in a model of extrapulmonary lung injury induced by sepsis. SN - 1364-8535 UR - https://doi.org/10.1186/cc9063 DO - 10.1186/cc9063 ID - Silva2010 ER -