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Table 4 Performance of multivariable models for the prediction of death, ICU or complication in CAP patients (n = 925)

From: Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections

Endpoint Model Bootstrap-corrected accuracy measure Leave-one-hospital-out cross-validation
Accuracy calculated on left out hospital
    Mean Range
Serious complication* CURB covariates    
  -AUC 0.75 0.75 0.67 to 0.83
  -Brier score 0.11 0.11 0.09 to 0.15
  CURB covariates + proADM    
  -AUC 0.76 0.76 0.72 to 0.81
  -Brier score 0.10 0.11 0.09 to 0.14
  CURB covariates + all biomarkers    
  -AUC 0.76 0.76 0.71 to 0.81
  -Brier score 0.11 0.11 0.09 to 0.14
Death CURB covariates    
  -AUC 0.80 0.81 0.72 to 0.87
  -Brier score 0.05 0.05 0.03 to 0.07
  CURB covariates + proADM    
  -AUC 0.81 0.82 0.71 to 0.87
  -Brier score 0.05 0.05 0.03 to 0.07
  CURB covariates + all biomarkers    
  -AUC 0.80 0.81 0.72 to 0.88
  -Brier score 0.05 0.05 0.03 to 0.07