Table 1 Characteristics of CAP patients at admission (n = 925)
Characteristics | All CAP patients (n = 925) | Serious complications (n = 134) | No serious complications (n = 791) | P | AUC |
|---|---|---|---|---|---|
Demographic characteristics | Â | Â | Â | Â | Â |
-Age (years)* | 72 (59 to 82) | 74 (62 to 82) | 72 (58 to 82) | 0.33 | 0.53 |
- Sex (male) - no. (%) | 544 (58.8) | 87 (64.9) | 457 (57.8) | 0.12 | Â |
Coexisting illnesses - no. (%) | Â | Â | Â | Â | Â |
-Coronary heart disease | 183 (19.8) | 38(28.4) | 145 (18.3) | 0.007 | - |
-Renal dysfunction | 206 (22.3) | 58 (43.3) | 148 (18.7) | <0.001 | - |
-COPD | 282 (30.5) | 58 (43.3) | 224(28.3) | 0.001 | - |
Clinical findings | Â | Â | Â | Â | Â |
-Confusion - no. (%) | 87 (9.4) | 19 (14.2) | 68 (8.6) | 0.04 | - |
-Respiratory rate (breaths/minute)* | 20 (16 to 25) | 24 (18 to 30) | 20 (16 to 25) | <0.001 | 0.63 |
-Systolic blood pressure (mmHg)* | 132 (119 to 148) | 120 (105 to 140) | 134 (120 to 150) | <0.001 | 0.62 |
-Heart rate (beats/minute)* | 95 (82 to 108) | 99 (81 to 114) | 94/102 to 106) | 0.02 | 0.56 |
-Body temperature (C°)* | 38.1 (37.2 to 38.9) | 38.0 (37.1 to 38.7) | 38.1 (37.3 to 38.9) | 0.19 | 0.53 |
Biomarkers | Â | Â | Â | Â | Â |
-Procalcitonin (μg/l)* | 0.71 (0.44 to 1.53) | 1.12 (0.66 to 2.39) | 0.66 (0.43 to 1.41) | <0.001 | 0.66 |
-ProADM (nmol/l)* | 1.1 (0.9 to 1.3) | 1.4 (1.1 to 1.8) | 1.1 (0.9 to 1.3) | <0.001 | 0.72 |
-ProANP (pmol/l)* | 9.1 (7.1 to 12.1) | 11.2 (8.2 to 14.4) | 8.7 (6.7 to 11.7) | <0.001 | 0.65 |
-ProET1 (pmol/l)* | 7.8 (6.7 to 9.3) | 9.6 (7.6 to 11.3) | 7.6 (6.6 to 8.9) | <0.001 | 0.72 |
-Copeptin (pmol/l)* | 4.0 (3.0 to 5.5) | 5.4 (4.0 to 8.2) | 3.8 (2.9 to 5.2) | <0.001 | 0.70 |
Risk assessment at admission | Â | Â | Â | Â | Â |
-PSI points* | 94 (67 to 116) | 116 (95 to 141) | 91/67 to 116) | <0.001 | 0.69 |
-PSI class* | 4 (2 to 4) | 4 (4 to 5) | 4 (2 to 4) | <0.001 | 0.67 |
-CURB-65 points* | 2 (1 to 2) | 2 (1 to 3) | 2 (1 to 2) | <0.001 | 0.66 |