Figure 5

Elevated endothelial microparticles in patients after CPR. Levels of endothelial microparticles (EMPs) in peripheral blood obtained immediately after restoration of cardiopulmonary resuscitation (CPR; left) and 24 hours after return to spontaneous circulation (right) from healthy subjects (white bars), patients with coronary artery disease (CAD; grey bars) and after CPR (black bars). The number of EMPs in resuscitated patients immediately after return to spontaneous circulation was slightly higher compared with both control groups, showing a significant difference compared with controls 24 hours after return to spontaneous circulation). There is a significant rise in EMPs when comparing the two points in time after return to spontaneous circulation in the resuscitation group, reflecting an ongoing endothelial damage in the first 24 hours after CPR. *** P < 0.001 versus control; ** P < 0.005 versus control; * P < 0.01 versus control; ns, statistically not significant versus control.