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Figure 3 | Critical Care

Figure 3

From: Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts

Figure 3

Time-dependent cytokine release in cardiac surgery patients. Timepoints were defined as: preoperative (0), immediately postoperative (4 to 6 hours), first postoperative day (24 hours), 2nd (48 hours) and 3rd postoperative day (72 hours). Samples were taken between 7:00 and 9:00 a.m. except postoperatively. Different genotype groups (DSNP = Mal/TLR4 combination, light grey bars; Mal[hom] = TIRAP/Mal-homozygous, grey bars; TLR4 = patients with TLR4-SNPs, dark grey bars; WT = wild-type patients, black bars). There were no statistical differences between the genotype groups at the timepoints. All values are shown as median and interquartile range.

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Critical Care

ISSN: 1364-8535