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Figure 1 | Critical Care

Figure 1

From: Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts

Figure 1

Impact of TIRAP/Mal or TLR4 polymorphisms or their combinations on circulating cytokine levels. Cytokine serum levels (pg/ml) were measured on day 1 after diagnosis of ventilator-associated pneumonia in Group II. Values are shown as median +/- 95% confidence interval (CI) and as mean +/- standard error. Number of patients in each group: Controls = 106, TIRAP/Mal (heterozygotes and homozygotes reported together) = 41, TIRAP/Mal-TLR4 = 3, TLR4 = 9. P values refer to significant differences compared with patients bearing the wild-type for all tested polymorphisms. Comparison calculated with Mann-U Whitney test. In this figure TIRAP/Mal is named TIRAP for readability.

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Critical Care

ISSN: 1364-8535