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Table 3 Patient therapies

From: Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry

 

VASOPRESSOR-YES

(N = 7,160)

VASOPRESSOR-NO

(N = 1,808)

TOTAL

(N = 8,968)

Variable, n (%)

LDC

(N = 2,794)

Non-LDC

(N = 4,366)

P -value

LDC

(N = 257)

Non-LDC

(N = 1,551)

P -value

LDC

(N = 3,051)

Non-LDC

(N = 5,917)

P- value

IV Fluid Resuscitation

2,645 (94.7)

3,944 (90.3)

<0.001

174 (67.7)

1,022 (65.9)

0.579

2,819 (92.4)

4,966 (83.9)

<0.001

Mechanical Ventilation

2,628 (94.1)

3,809 (87.2)

<0.001

173 (67.3)

934 (60.2)

0.031

2,801 (91.8)

4,743 (80.2)

<0.001

Nutrition: Enteral

2,133 (76.3)

2,984 (68.3)

<0.001

181 (70.4)

1,125 (72.6)

0.473

2,314 (75.8)

4,109 (69.4)

<0.001

Nutrition: Parenteral

1,293 (46.3)

1,350 (30.9)

<0.001

106 (41.2)

295 (19.0)

<0.001

1,399 (45.9)

1,645 (27.8)

<0.001

Heparin: LMW

1,203 (43.1)

1,552 (35.6)

<0.001

119 (46.3)

455 (29.3)

<0.001

1,322 (43.3)

2,007 (33.0)

<0.001

Heparin: Unfractionated

1,287 (46.1)

1,452 (33.3)

<0.001

48 (18.7)

454 (29.3)

<0.001

1,335 (43.8)

1,906 (32.2)

<0.001

Mechanical VTE Prophylaxis

671 (24.0)

1116 (25.6)

0.091

77 (30.0)

234 (15.1)

<0.001

748 (24.5)

1,350 (22.8)

0.107

Renal Replacement Therapy

875 (31.3)

839 (19.2)

<0.001

20 (7.8)

142 (9.2)

0.474

895 (29.3)

981 (16.6)

<0.001

Platelet Transfusion

579 (20.7)

696 (15.9)

<0.001

22 (8.6)

82 (5.3)

0.037

601 (19.7)

778 (13.2)

<0.001

DAA Therapy

313 (11.2)

234 (5.4)

<0.001

13 (5.1)

23 (1.7)

<0.001

326 (10.7)

257 (4.3)

<0.001

  1. P-values are from the Chi-Square test.
  2. LDC, low-dose corticosteroids, IV, intravenous, LMW, low-molecular weight, VTE, venous thromboembolism, DAA, Drotrecogin alfa (activated).