Skip to main content

Table 1 Comparison of patients with normal and elevated cardiac troponin I (cTnI)

From: Elevation of cardiac troponin I during non-exertional heat-related illnesses in the context of a heatwave

Variable Normal cTni
(n = 252)
Elevated cTnI
(n = 62)
P % missing g values*
Age (years) 83 ± 11 85 ± 12 0.18 0%
Age >80 years 179/252 (71) 199/262 (76) 0.23 0%
Male sex 109/252 (43) 87/262 (33) 0.02 0%
Katz index 6 (3 to 6) 5 (2 to 6) 0.006 20.4%
Living in an institution 48/252 (19) 63/262 (24) 0.24 0%
Transportation to the hospital in an ambulance 241/252 (96) 253/262 (96) 1.00 0%
Pre-existing disease     
   Hypertension 100/249 (40) 86/256 (33) 0.14 1.8%
   Coronary artery disease 57/249 (23) 89/256 (35) 0.004 1.8%
   Heart failure 29/249 (12) 30/256 (12) 1.00 1.8%
   Diabetes 32/249 (13) 35/256 (14) 0.79 1.8%
   Cancer 30/249 (12) 12/256 (5) 0.003 1.8%
Chronic medications     
   Diuretics 85/247 (34) 92/247 (37) 0.57 3.9%
   CEI or AII I 51/247 (21) 60/247 (24) 0.39 3.9%
   Beta-blockers 39/247 (16) 27/247 (11) 0.15 3.9%
   Calcium inhibitors 38/247 (15) 45/247 (18) 0.47 3.9%
   Nitrates 35/247 (14) 61/247 (24) 0.004 3.9%
   Inotropic drugs 25/247 (10) 35/247 (14) 0.21 3.9%
   Antiarrhythmic drugs 33/247 (13) 19/247 (8) 0.06 3.9%
   Anticoagulant or antiaggregants 110/247 (44) 101/247 (41) 0.47 3.9%
   Statines 20/247 (8) 14/247 (6) 0.37 3.9%
Clinical signs     
   Core temperature (°C) 39.9 ± 1.1 40.6 ± 1.3 <0.001 0%
   Core temperature >40°C 105/252 (42) 176/262 (67) <0.001 0%
   SBP (mmHg) 120 ± 37 104 ± 42 <0.001 0%
   SBP <100 mmHg 31/214 (12) 74/254 (29) <0.001 0%
   Glasgow coma scale 15 (13 to 15) 12 (6 to 15) <0.001 10.0%
   Glasgow coma scale <12 41/227 (18) 118/237 (50) <0.001 10.0%
   Oxygen saturation (%) 93 (90 to 96) 92 (88 to 95) 0.01 26.5%
   Oxygen saturation <90% † 36/173 (21) 66/205 (32) 0.015 26.5%
Biological variables (blood)     
   Leucocytes (G/L) 12,128 ± 8,914 13,834 ± 6,902 0.017 3.2%
   Plasma sodium (mmol/L) 137 ± 9 138 ± 11 0.08 1.8%
   Hypernatremia (>145 mmol/L) 33/250 (13) 49/255 (19) 0.07 1.8%
   Creatinine (μmol/L) 119 ± 66 155 ± 85 <0.001 1.9%
   Creatinine >120 μmol/L 93/247 (38) 155//257 (64) <0.001 1.9%
   Bicarbonates (mmol/L) 24.6 ± 4.0 22.1 ± 4.5 <0.001 3.5%
   Arterial pH 7.42 ± 0.05 7.39 ± 0.10 0.006 89.5%
Infection 93/248 (37) 79/259 (30) 0.11 1.4%
Therapeutic cooling 181/252 (72) 195/262 (74) 0.55 0%
Admitted to ICU 9/252 (4) 26/262 (10) 0.005 0%
Critically ill 47/247 (19) 134/259 (52) <0.001 1.6%
Risk score 8 (6 to 11) 12 (8 to 16) <0.001 15.9%
Risk score categories §     
   - low 63/228 (28) 27/238 (11)   
   - intermediate 128/228 (56) 101/238 (42) <0.001 9.3%
   - high 37/228 (16) 110/238 (46)   
  1. Data are mean + SD, median [25 to 75 interquartile, or number (%).
  2. †, measured using pulse oximetry. *, % of missing values were provided for the global population (no significant differences between the two groups). ¶ despite some missing values precludes exact calculation of the risk score, the risk score category could be allocated to 34 patients because these missing values were not able to modify it.
  3. AII I: angiotensin II inhibitors; CEI: converting enzyme inhibitor; SBP: systolic arterial blood pressure.