Skip to main content

Table 4 Variation in relative differences in total costs between on-demand and planned relaparotomy strategies across various clinical subgroups

From: Costs of relaparotomy on-demand versus planned relaparotomy in patients with severe peritonitis: an economic evaluation within a randomized controlled trial

 

Relaparotomy strategy

  
  

On demand

 

Planned

Differencea

 
 

Mean costs p.p.

n

Mean costs p.p.

n

% from planned

P valueb

Overall

66,216

112

84,152

113

-23.8%

 

Comorbidity

     

0.26

   No

64,948

48

89,738

41

-32.8%

 

   Yes

67,168

64

80,971

72

-17.1%

 

Apache II

     

0.58

   11-20

66,956

96

84,683

94

-22.3%

 

   >20

61,777

16

81,525

19

-32.3%

 

Etiology

     

0.09

   Inflammation (1)

40,810

4

81,074

5

-21.7%

 

   Perforation (2)

62,236

63

88,985

67

-37.0%

 

   Ischemia (1)

59,591

6

72,080

8

--

 

   Anastomotic leakage (3)

76,171

35

72,751

27

6.8%

 

   Other (4)

77,153

4

100,149

6

-6.9%

 

   Elimination of infectious source

     

0.81

   No

71,113

10

90,254

11

-24.2%

 

   Yes

65,736

102

83,494

102

-18.3%

 

Localization

     

0.45

   Upper GT (1)

69,828

30

81,146

27

-25.9%

 

   Lower GT (2)

67,402

70

82,446

74

-42.7%

 

   Biliary tract (3)

63,496

2

100,115

5

-28.8%

 

   Appendix (3)

32,075

3

26,575

1

--

 

   Pancreas (3)

59,352

5

92,446

2

--

 

   Gynecol (3)

41,650

2

67,720

1

--

 

   Other (3)

  

145,821

3

--

 

Extent of index operation

     

0.49

   1 quadrant

66,079

9

73,381

16

3.0%

 

   2 quadrants

62,439

34

84,791

26

-30.6%

 

   Diffuse

68,096

70

86,102

69

-24.8%

 

Nature of contamination

     

0.18

   Clear (1)

59,306

6

97,791

8

-25.9%

 

   Turbid (2)

57,179

18

96,672

29

-42.7%

 

   Purulent (3)

55,746

43

77,003

30

-28.8%

 

   Fecal (4)

84,707

41

81,977

41

-2.4%

 

   Bile (3)

40,281

4

61,984

3

-

 

Survival (at 12 mo)

      

   No

73,275

80

85,326

72

-17.8%

0.13

   Yes

48,569

32

82,089

41

-38.6%

 
  1. aModel estimates of difference between On demand and Planned relaparotomy strategy based on analyses of geometric means; bFor the interaction effect in regression model; (x) numbers between brackets indicate collapsed categories used as interaction effect. The P value for the interaction effect in the regression model tests the hypothesis that the relative differences between the two surgical strategies are the same across clinical subgroups (for example, for comorbidity, that -32.8% = -17.1%). P values > 0.05 indicate that this hypothesis cannot be rejected at a 5% statistical significance level.