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Table 1 Baseline patient characteristics and ghrelin serum concentrations

From: Regulation and prognostic relevance of serum ghrelin concentrations in critical illness and sepsis

Parameter

All patients

Sepsis

non-Sepsis

Number

170

122

48

Sex (male/female) n

111/59

81/41

30/18

Age median (range) (years)

63

(18 to 86)

64

(20 to 86)

60

(18 to 79)

APACHE-II score median (range)

14

(0 to 31)

14

(0 to 31)

15

(0 to 31)

SAPS2 score median (range)

44

(0 to 80)

45

(0 to 79)

41

(13 to 80)

ICU days median (range)

8.5

(1 to 137)

10

(1 to 137)

6

(1 to 45)

Hospital days median (range)

27

(2 to 151)

30

(2 to 151)

14

(2 to 85)

Death during ICU n(%)

54 (32%)

42 (34%)

12 (25%)

Death during follow-up n(%)

88 (52%)

64 (53%)

24 (50%)

30-day mortality [%]

32%

32%

31%

60-day mortality [%]

39%

40%

35%

90-day mortality [%]

42%

44%

35%

180-day mortality [%]

45%

48%

38%

1-year mortality [%]

49%

51%

44%

Mechanical ventilation n(%)

113 (67%)

82 (67%)

31 (65%)

Ventilation time median (range) [h]

66

(1 to 2,966)

127.5

(1 to 2,966)

31

(1 to 755)

pre-existing diabetes n(%)

56 (33%)

39 (32%)

17 (35%)

BMI median (range) (m²/kg)

25.8

(14.0 to 59.5)

26.0

(14.0 to 59.5)

25.1

(17.5 to 53.3)

Serum IGF-1 median (range) (μg/L)

54

(25 to 295)

54

(25 to 295)

49

(25 to 165)

Serum growth hormone median (range) (μg/L)

1.5

(0.1 to 128.0)

1.3

(0.1 to 128.0)

2.0

(0.1 to 22.3)

Serum ghrelin median (range) (pmol/L)

18.4

(5.0 to 129.5)

18.4

(5 to 113.8)

18.4

(5 to 129.5)

  1. APACHE: acute physiology and chronic health evaluation; BMI: body mass index; IGF-1, insulin-like growth factor-1; SAPS: simplified acute physiology score