Table 2 Baseline measurements according to disease category

N

52

31

41

Angiopoietin 2 (ng/ml) ^a

12.44 (8.47-33.44)

6.11 (4.59-10.37)

2.71 (2.15-3.61)

0.0001^d

VEGF (pg/ml) ^a

98.4 (56.4-142.6)

80.8 (57.5-147.3)

52.3 (31.8-73.5)

0.0007^d

Plasma ICAM-1 (ng/ml) ^a

846 (523-1483)

501 (368-672)

323 (265-393)

0.0001^d

Plasma E-selectin (ng/ml) ^a

200.5 (113-478)

87.0 (50.8-164.4)

38.4 (26.9-58.2)

0.0001^d

RH-PAT index ^b

1.57 (1.44-1.71)

1.85 (1.67-2.03)

2.07 (1.93-2.22)

<0.0001^e

Plasma interleukin 6 (pg/ml) ^a

385.1 (124.2-996.0)

148.3 (45.9-315.0)

5.0 (2.2-8.1)

0.0001^d

Plasma TNFα ≥ 2.8 pg/ml (n,%) ^c

8 (22)

4 (14)

5 (17)

NS^f