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Table 2 General patient information

From: Reducing mortality in severe sepsis with the implementation of a core 6-hour bundle: results from the Portuguese community-acquired sepsis study (SACiUCI study)

    Severity of sepsis   28-days outcome  
  Total(n = 778) Severe sepsis (n = 341) Septic shock (n = 437) P value Death (n = 257) Alive (n = 521) P value
Age, mean (SD) 61 (17) 59 (18) 63 (16) 0.009 # 64 (16) 60 (17) <0.001 #
Gender, n (%)             
   Female 280 (36) 129 (38) 151 (35) 0.345* 80 (31) 200 (38) 0.047*
   Male 498 (64) 212 (62) 286 (65)   177 (69) 321 (62)  
SAPS II, mean (SD) 51 (19) 44 (15) 57 (19) <0.001 # 62 (21) 46 (16) <0.001 #
Diagnosis on admission, n (%)             
   Medical 634 (81) 289 (85) 345 (79) - 214 (83) 420 (81) -
   Trauma 6 (1) 3 (1) 3 (1)   0 (0) 6 (1)  
   Surgical 138 (18) 49 (14) 89 (20)   43 (17) 95 (18)  
Focus of infection, n (%)             
   Respiratory 458 (59) 227 (66) 231 (53) <0.001* 144 (56) 314 (60) 0.183*
   Urinary 60 (8) 20 (6) 40 (9)   15 (6) 45 (9)  
   Intra-abdominal 147 (19) 40 (12) 107 (24)   56 (22) 91 (17)  
   Other 113 (14) 54 (16) 59 (14)   42 (16) 71 (14)  
Number of comorbidities, n (%)             
   0 369 (48) 150 (45) 219 (51) 0.212* 105 (41) 264 (51) 0.018*
   1 207 (27) 93 (28) 114 (26)   73 (29) 134 (26)  
   >1 193 (25) 93 (28) 100 (23)   77 (30) 116 (23)  
ICU length of stay, med (IQR) 9 (5-16) 8 (5-15) 10 (5-17) 0.483£ 6 (3-14) 10 (7-17) <0.001 £
28-day mortality, n (%) 257 (33) 66 (19) 191 (44) <0.001*      
  1. Differences in the patient profile according to the severity of sepsis (severe sepsis and septic shock) and 28 days outcome (death or alive) are shown.
  2. IQR: interquartile range; SAPS: Simplified Acute Physiological Score; SD: standard deviation.
  3. # t-test; * Pearson chi-square test; £ Mann-Whitney Test.