Severity of sepsis | 28-days outcome | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Total(n = 778) | Severe sepsis (n = 341) | Septic shock (n = 437) | P value | Death (n = 257) | Alive (n = 521) | P value | ||||||
Age, mean (SD) | 61 | (17) | 59 | (18) | 63 | (16) | 0.009 # | 64 | (16) | 60 | (17) | <0.001 # |
Gender, n (%) | ||||||||||||
Female | 280 | (36) | 129 | (38) | 151 | (35) | 0.345* | 80 | (31) | 200 | (38) | 0.047* |
Male | 498 | (64) | 212 | (62) | 286 | (65) | 177 | (69) | 321 | (62) | ||
SAPS II, mean (SD) | 51 | (19) | 44 | (15) | 57 | (19) | <0.001 # | 62 | (21) | 46 | (16) | <0.001 # |
Diagnosis on admission, n (%) | ||||||||||||
Medical | 634 | (81) | 289 | (85) | 345 | (79) | - | 214 | (83) | 420 | (81) | - |
Trauma | 6 | (1) | 3 | (1) | 3 | (1) | 0 | (0) | 6 | (1) | ||
Surgical | 138 | (18) | 49 | (14) | 89 | (20) | 43 | (17) | 95 | (18) | ||
Focus of infection, n (%) | ||||||||||||
Respiratory | 458 | (59) | 227 | (66) | 231 | (53) | <0.001* | 144 | (56) | 314 | (60) | 0.183* |
Urinary | 60 | (8) | 20 | (6) | 40 | (9) | 15 | (6) | 45 | (9) | ||
Intra-abdominal | 147 | (19) | 40 | (12) | 107 | (24) | 56 | (22) | 91 | (17) | ||
Other | 113 | (14) | 54 | (16) | 59 | (14) | 42 | (16) | 71 | (14) | ||
Number of comorbidities, n (%) | ||||||||||||
0 | 369 | (48) | 150 | (45) | 219 | (51) | 0.212* | 105 | (41) | 264 | (51) | 0.018* |
1 | 207 | (27) | 93 | (28) | 114 | (26) | 73 | (29) | 134 | (26) | ||
>1 | 193 | (25) | 93 | (28) | 100 | (23) | 77 | (30) | 116 | (23) | ||
ICU length of stay, med (IQR) | 9 | (5-16) | 8 | (5-15) | 10 | (5-17) | 0.483£ | 6 | (3-14) | 10 | (7-17) | <0.001 £ |
28-day mortality, n (%) | 257 | (33) | 66 | (19) | 191 | (44) | <0.001* |