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Table 4 Multivariate logistic regression analysis of MODS, septic shock and ICU mortality

From: 4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study

  MODS   Septic shock   ICU mortality  
  Odds ratio
(95% confidence interval)
p value Odds ratio
(95% confidence interval)
p value Odds ratio
(95% confidence interval)
p value
Age, years 1.048 (1.027-1.069) <0.001 1.032 (1.013-1.052) 0.001 - -
Nosocomial infection 3.029 (1.503-6.102) 0.002 2.047 (1.104-3.797) 0.023 - -
Positive microbiological culture 3.642 (1.876-7.069) <0.001 2.365 (1.275-4.386) 0.006 - -
APACHE II - - - - 1.158 (1.101-1.217) <0.001
PAI-1       
5G/5G reference group   reference group   reference group  
4G/5G and 4G/4G 2.957 (1.306-6.698) 0.009 2.603 (1.137-5.959) 0.024 1.998 (0.879-4.540) 0.098
  1. APACHE II, acute physiology and chronic health evaluation II; MODS, multiple organ dysfunction syndrome.