Table 3 Distribution of PAI-1 4G/5G genotypes and alleles as stratified according to multiple organ dysfunction, sepsis severity and mortality
Multiple organ dysfunction | Sepsis severity | ICU mortality | |||||||
|---|---|---|---|---|---|---|---|---|---|
Non-MODS (n = 86) | MODS (n = 121) | p value* | Severe sepsis (n = 118) | Septic shock (n = 89) | p value* | Survivors (n = 129) | Non-survivors (n = 78) | p value* | |
Genotype | |||||||||
4G/4G and 4G/5G | 62 (72.1%) | 106 (87.6%) | 89 (75.4%) | 79 (88.8%) | 100 (77.5%) | 68 (87.2%) | |||
5G/5G | 24 (27.9%) | 15 (12.4%) | 0.005 | 29 (24.6%) | 10 (11.2%) | 0.015 | 29 (22.5%) | 10 (12.8%) | 0.085 |
Allele | |||||||||
4G | 86 (50.0%) | 145 (59.9%) | 120 (50.8%) | 111 (62.4%) | 136 (52.7%) | 95 (60.9%) | |||
5G | 86 (50.0%) | 97 (40.1%) | 0.045 | 116 (49.2%) | 67 (37.6%) | 0.019 | 122 (47.3%) | 61 (39.1%) | 0.104 |