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Table 1 Laboratory parameters (mean ± standard deviation). Parameters included in the table are haemoglobin, platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT) and thrombin-AT complex (TAT) at baseline, after haemodilution, after fibrinogen substitution (fibrinogen) at the end of the observation period (trauma)

From: Effects of different fibrinogen concentrations on blood loss and coagulation parameters in a pig model of coagulopathy with blunt liver injury

  Baseline Haemodilution Fibrinogen Trauma
Haemoglobin (g L-1)     
   Control 8.2 ± 0.5 7.5 ± 0.6 7.8 ± 0.4 3.7 ± 0.4
   F-70 8.1 ± 0.4 7.7 ± 0.4 7.9 ± 0.6 4.1 ± 0.3
   F-200 8.0 ± 0.2 8.0 ± 0.6 8.0 ± 0.5 4.5 ± 1.7
PLT (103 μL-1)     
   Control 268 ± 35 85 ± 8 84 ± 11 46 ± 4
   F-70 263 ± 44 87 ± 10 87 ± 13 54 ± 14
   F-200 294 ± 41 94 ± 11 95 ± 12 71 ± 10*
aPTT (s)     
   Control 12 ± 1 22 ± 5 22 ± 5 27 ± 6
   F-70 11 ± 2 24 ± 6 22 ± 5 28 ± 3
   F-200 11 ± 1 23 ± 2 20 ± 2 21 ± 5
TAT (μg L-1)     
   Control 10.4 ± 3.2 11.3 ± 3.5 10.4 ± 3.0 17.4 ± 6.7
   F-70 8.0 ± 3.0 8.1 ± 1.6 9.1 ± 1.5 12.9 ± 5.5
   F-200 10.2 ± 2.8 8.5 ± 5.7 8.4 ± 2.9 12.3 ± 2.0
  1. *P < 0.005 F-200 vs. control.