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Table 1 Laboratory parameters (mean ± standard deviation). Parameters included in the table are haemoglobin, platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT) and thrombin-AT complex (TAT) at baseline, after haemodilution, after fibrinogen substitution (fibrinogen) at the end of the observation period (trauma)

From: Effects of different fibrinogen concentrations on blood loss and coagulation parameters in a pig model of coagulopathy with blunt liver injury

 

Baseline

Haemodilution

Fibrinogen

Trauma

Haemoglobin (g L-1)

    

   Control

8.2 ± 0.5

7.5 ± 0.6

7.8 ± 0.4

3.7 ± 0.4

   F-70

8.1 ± 0.4

7.7 ± 0.4

7.9 ± 0.6

4.1 ± 0.3

   F-200

8.0 ± 0.2

8.0 ± 0.6

8.0 ± 0.5

4.5 ± 1.7

PLT (103 μL-1)

    

   Control

268 ± 35

85 ± 8

84 ± 11

46 ± 4

   F-70

263 ± 44

87 ± 10

87 ± 13

54 ± 14

   F-200

294 ± 41

94 ± 11

95 ± 12

71 ± 10*

aPTT (s)

    

   Control

12 ± 1

22 ± 5

22 ± 5

27 ± 6

   F-70

11 ± 2

24 ± 6

22 ± 5

28 ± 3

   F-200

11 ± 1

23 ± 2

20 ± 2

21 ± 5

TAT (μg L-1)

    

   Control

10.4 ± 3.2

11.3 ± 3.5

10.4 ± 3.0

17.4 ± 6.7

   F-70

8.0 ± 3.0

8.1 ± 1.6

9.1 ± 1.5

12.9 ± 5.5

   F-200

10.2 ± 2.8

8.5 ± 5.7

8.4 ± 2.9

12.3 ± 2.0

  1. *P < 0.005 F-200 vs. control.