Severe trauma victim (otherwise precluding normal care) |
Suffered from severe burns with either of these two criteria: |
   40% burn of total body surface area |
   Inhalation injury |
Cardiac arrest (ongoing at time of evaluation) |
Severe baseline cognitive impairment |
   Defined as requiring regular ongoing assistance from others |
Advanced significant and/or untreatable neurological disease with major functional impairment |
Presence of metastatic and/or terminal cancer |
Advance immunocompromised state, for example: |
   End-stage renal disease |
   AIDS |
   Status post-organ transplant requiring ongoing immunosuppressive therapy |
Evidence of end-stage organ failure: |
   Heart: NYHA class 3 or 4 heart failure |
   Lungs: COPD requiring chronic oxygen therapy, cystic fibrosis with baseline PaO2 <55 mmHg, primary pulmonary hypertension with pulmonary arterial pressure >50 mmHg |
   Liver: current liver failure or chronic liver disease with Child-Pugh score ≥7 |
   Kidney: renal failure requiring dialysis |