Table 3 Evolution of the patients with normal kidney function and RIFLE class 'risk' on admission broken by HES administration
Normal kidney function on admission | P | RIFLE "risk" on admission | P | |||
|---|---|---|---|---|---|---|
HES - n = 45 | HES + n = 28 | HES - n = 54 | HES + n = 37 | |||
ICU treatments | ||||||
Catecholamines n (%) | 17 (37.7) | 19 (67.9) | 0.01 | 27 (50) | 27 (73) | 0.03 |
- Norepinephrine | 15 (33.3) | 18 (64.3) | 0.01 | 26 (48.1) | 25 (67.6) | 0.07 |
- Epinephrine | 1 (2.2) | 3 (10.7) | 0.12 | 2 (3.7) | 2 (5.4) | 1 |
- Dobutamine | 3 (6.7) | 4 (14.3) | 0.41 | 3 (5.5) | 4 (10.8) | 0.43 |
Activated protein C | 0 (0) | 0 (0) | 1 | 0 (0) | 0 (0) | 1 |
Hydrocortisone | 7 (15.5) | 7 (25) | 0.7 | 14 (25.9) | 13 (35.1) | 0.92 |
Mechanical ventilation | 28 (62.2) | 24 (85.7) | 0.03 | 36 (66.7) | 33 (89.2) | 0.01 |
Aminoglycosides | 8 (17.8) | 9 (32.1) | 0.16 | 15 (27.8) | 13 (35.1) | 0.45 |
Toxic dose aminoglycosides | 1 (2.2) | 1 (3.6) | 1 | 0 (0) | 0 (0) | 1 |
Glycopeptides | 7 (15.5) | 6 (21.4) | 0.54 | 13 (24.1) | 12 (32.4) | 0.38 |
Toxic dose glycopeptides | 1 (2.2) | 0 (0) | 1 | 3 (5.5) | 1 (2.7) | 0.64 |
Amphotericin B | 0 (0) | 0 (0) | 1 | 0 (0) | 0 (0) | 1 |
Radio-contrast agents | 7 (15.5) | 4 (14.3) | 1 | 5 (9.2) | 5 (13.5) | 0.73 |
Rhabdomyolysis | 4 (8.9) | 3 (10.7) | 1 | 6 (11.1) | 6 (16.2) | 0.47 |
Urinary obstruction | 1 (2.2) | 0 (0) | 1 | 0 (0) | 1 (2.7) | 0.4 |
Chemotherapy | 0 (0) | 0 (0) | 1 | 0 (0) | 1 (2.7) | 0.4 |
Evolution | ||||||
Shock from day 3 to day 21 | 3 (6.7) | 4 (14.3) | 0.41 | 6 (11.1) | 6 (16.2) | 0.54 |
Hemofiltration | 0 (0) | 2 (7.1) | 0.14 | 3 (5.5) | 3 (8.1) | 0.68 |
AKI | 5 (11.1) | 5 (17.9) | 0.49 | 6 (11.1) | 3 (8.1) | 0.73 |
Nosocomial infection | 8 (17.8) | 8 (28.6) | 0.28 | 11 (20.4) | 10 (27) | 0.45 |
Duration of shock (days (mean ± SD)) | 1.4 ± 2.6 | 4.2 ± 6.1 | 0.004 | 2.1 ± 3.1 | 3.8 ± 4.2 | 0.01 |
Duration of mechanical ventilation (days) | 8.4 ± 11.5 | 16.4 ± 18.6 | 0.02 | 13.3 ± 17.2 | 12.8 ± 16.8 | 0.1 |
Duration of hemofiltration (days) | 0 | 1.2 ± 4.3 | 0.07 | 0.9 ± 5.2 | 0.7 ± 2.8 | 0.38 |
Duration of ICU stay (days) | 12.5 ± 12.7 | 20.2 ± 20.3 | 0.09 | 14.8 ± 16.6 | 15.4 ± 16.6 | 0.27 |
ICU death | 9 (20) | 7 (25) | 0.62 | 12 (22.2) | 12 (32.4) | 0.28 |