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Table 2 Ventilatory parameters and arterial blood gases

From: Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease

 

High V T Group

Low V T Group

Time

Zero

12 h

Zero

12 h

VT (PBW) (ml)

11.3 ± 0.8**

11.9 ± 0.9*

6.2 ± 0.6

6.2 ± 0.7

Peak Pressure (cmH2O)

29.80 ± 8.74**

29.6 ± 7.39**

17.90 ± 2.80

17.60 ± 3.34

Plateau Pressure (cmH2O)

28.90 ± 8.71**

28.60 ± 7.32**

17.10 ± 3.03

16.70 ± 3.26

PEEP (cmH2O)

4.30 ± 0.48

4.30 ± 0.48

4.50 ± 0.52

4.50 ± 0.52

Ventilatory rate (bpm)

18.6 ± 1.4 *

18.7 ± 1.4*

20.7 ± 2.5

21.3 ± 2.2

FIO2 (%)

52.50 ± 25.41

48.50 ± 19.58

41.00 ± 2.10

41.00 ± 2.10

pH

7.38 ± 0.04

7.41 ± 0.06

7.39 ± 0.05

7.40 ± 0.04

PaO2 (mmHg)

143.60 ± 30.52

133.70 ± 32.92

146.00 ± 81.83

119.80 ± 28.76

PaCO2 (mmHg)

34.40 ± 7.32

26.60 ± 5.60

30.29 ± 8.28

31.45 ± 7.18

HCO3 (mmol/L)

20.80 ± 6.01

17.89 ± 5.56

19.71 ± 4.58

21.42 ± 5.56

SaO2 (%)

98.00 ± 2.58

98.30 ± 2.16

97.60 ± 2.27

97.90 ± 2.18

PaO2/FIO2

307 ± 101

298 ± 105

358 ± 207

293 ± 74

  1. FIO2, inspiratory fraction of oxygen; HCO3, bicarbonate; PaCO2, partial pressure of carbon dioxide; PaO2, arterial oxygen tension; PBW, predicted body weight; PEEP, positive end expiratory pressure; SaO2, arterial oxygen saturation; VT, tidal volume; *P < 0.01, **P < 0.001 vs. Low VT group