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Table 2 Clinical characteristics for hospital survivors and non-survivors in patients with admission blood lactate concentration within the reference range

From: Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study

 

n

Hospital Non-survivors

n

Hospital Survivors

P-value

Male Sex

607

58.2% (353)

3,357

59% (1,981)

0.71

APACHE II score

485

22.1 (7.3)

2,891

14.2 (6.2)

< 0.0001

Age (yr)

556

66.0 (16.5)

3,090

60.7 (18.7)

< 0.0001

Number on mechanical ventilation

551

77.3% (426)

3,313

48.7% (1,613)

< 0.0001

Surgical patients

607

31% (188)

3,357

50.9% (1,709)

< 0.0001

Diagnosis at admission

     

Cardiac and vascular

607

15.2% (92)

3,357

20.4% (685)

0.003

Thoracic and respiratory

607

24.2% (147)

3,357

20% (671)

0.017

Trauma

607

3.6% (22)

3,357

8.8% (295)

< 0.0001

Neurological

607

18.1% (110)

3,357

10.9% (366)

< 0.0001

Gastrointestinal tract diseases

607

15.3% (93)

3,357

23.7% (796)

< 0.0001

Other

607

23.6% (143)

3,357

16.2% (544)

< 0.0001

ICU stay (days)

606

3.0 (2.0 to 8.0)

3,357

2.0 (1.3 to 4.0)

< 0.0001

Hospital stay (days)

501

12.9 (5.2 to 30.2)

3,064

13.0 (7.9 to 26.7)

0.041

Admission blood lactate (mmom.L -1 )

607

1.3 (1 to 1.6)

3,357

1.2 (0.9 to 1.5)

< 0.0001

Time-weighted blood lactate (mmom.L -1 )

599

1.4 (1.1 to 1.9)

3,212

1.20 (1.0 to 1.5)

< 0.0001

Max blood lactate (mmom.L -1 )

607

2.4 (1.6 to 4.1)

3,357

1.7 (1.3 to 2.4)

< 0.0001

  1. Data are expressed as, percentage (number), (standard deviation) or median (interquartile range) APACHE II, Acute Physiology and Chronic Health Evaluation II.